AKBAR KARKHANEH
Associate Professor
Department of Biomedical Engineering
Biomaterial
Department of Biomedical Engineering
Biomaterial
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Email:
a.karkhaneh
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h-index (Scopus):
26
Citations (Scopus):
2066
Supervised MSc Theses
#
Thesis title
By
Date
1
Experimental investigation of Nitric Oxide release from polysaccharide based wound dressings
Mahboube Shafiei & Akbar Karkhaneh
February 2024
2
Fabrication of piezoelectric three-dimension scaffold with oxygen release capability for use in bone tissue engineering applications
Nazanin Jafaripour & Akbar Karkhaneh
February 2024
3
Fabrication and characterization of a dual-drug loaded silk fibroin hydrogel for chemotherapy of glioblastoma and reconstruction of the cavity created after surgical resection
Nadia Shafaei & Akbar Karkhaneh
February 2024
4
Fabrication and characterization of alginate-based hydrogel wound dressing reinforced by lignin with drug release capability
Faeze Shojaeinia & Akbar Karkhaneh
July 2023
5
Optimization of the concurrent release of oxygen and dexamethasone by altering the microstructure of the polyester-based carrier
Sogol Younesi & Akbar Karkhaneh
February 2023
6
Investigating the effect of aloe vera on the release of dexamethasone from polyvinyl alcohol-based nanofibrous wound dressings
Armin Barghi & Akbar Karkhaneh
February 2023
7
Experimental investigation of osteogenic differentiation of mesenchymal stem cells, in an injectable scaffold with the capability of releasing oxygen and magnesium ions
Mina Maleki & Akbar Karkhaneh
June 2022
8
Design and fabrication of oxygen releasing system to reduce hypoxia induced drug resistance in cancer
Negar Akbari & Akbar Karkhaneh
June 2022
9
Fabrication of self-assembled nanocarriers, based on hydrophobically modified polysaccharides, for anti-cancer drug
Fatemeh Shabani & Akbar Karkhaneh
May 2022
10
Experimental investigation of magnesium ion release from photocrosslinkable hydrogel, functionalized with thiol groups, in bone tissue engineering
Seyyed Ahmad Seyyed Nasrollah & Akbar Karkhaneh
October 2021
11
Preparation of Micelle based on Amphiphilic Polysaccharide for Anti-cancer Drug Release
Nayereh Azimijou & Akbar Karkhaneh
October 2021
12
fabrication and characterization of poly pyrrole-based conductive hydrogel for tissue engineering application
Vahid Heidari & Akbar Karkhaneh
September 2020
13
Investigation of cell imprinting effect on inflammation reduction in chondrosarcoma
Zahra Bozorgmehr & Akbar Karkhaneh
February 2020
14
Fabrication and characterization of microparticles with oxygen-releasing material as bone tissue scaffold
Elham Mohseni Vadeghani & Akbar Karkhaneh
February 2020
15
Design and synthesis of particles with controlled release of oxygen
Sara Nejati & Akbar Karkhaneh
January 2020
16
Preparation and investigation of conductive hydrogel scaffolds reinforced with fibers coupled collagen for neural tissue engineering
Alireza Mahjoubnia & Akbar Karkhaneh
September 2019
17
An Investigation into curcumin release from PLA particles loaded in PCL-GELATIN fibers for skin application
Misagh Saadipour & Akbar Karkhaneh
July 2019
18
Preparation and evaluation of electrospun nanofibrous scaffolds based on gelatin and polypyrrole for nerve tissue engineering applications
Fatemeh Imani & Akbar Karkhaneh
February 2019
19
Fabrication and characterization of silk/pectin hydrogel scaffold containing PLLA nanofibers
Fereshteh Ahadi & Akbar Karkhaneh
October 2018
20
fabrication of silk- halloysite nanocompisites modified with vancomycin as bone tissue engineering scaffold
Farzaneh Aavani & Akbar Karkhaneh
January 2018
21
Fabrication and evaluation of nano-composite electrospun scaffold based on PCL, PVDF , HA with piezoelectric properties for bone tissue engineering
Narges Akbari & Akbar Karkhaneh
October 2017
22
the study of chondrocyte behaviors on the drug loaded scaffold under hydrostatic pressure
Sana Ansari & Akbar Karkhaneh
October 2017
23
The effect of Copper ion release from silk fibroin nanocomposite scaffolds on the behavior of Endothelial cells
Zahra Afzali & Akbar Karkhaneh
July 2017
24
Manufacturing and characterization of nanofibrous composite scaffold based on polypyrrole grafted cellulose acetate for neural tissue engineering application
Farnoosh Saeedinejad & Akbar Karkhaneh
October 2016
25
Manufacturing of nanofibrous scaffold containing stimulating drug for mesenchymal stem cell differentiation based on chitosan for cartilage tissue engineering
Neginsadat Yarandi & Akbar Karkhaneh
August 2016
26
Design and manufacturing of injectable conductive scaffold for cardiac tissue engineering
Farinaz Ketabat & Akbar Karkhaneh
February 2016
27
Design and preparation of alginate nanocarriers for oral drug delivery
Salime Bazban Shotorbani & Akbar Karkhaneh
February 2016
28
design and manufacture of alginate-gelatine-poly(3,4-ethlenedioxythiphene) poly (styrenesulfonate) scaffold to study the effect of electrical conducctivity on cell for ophthalnic application
Masoumeh Hesam Mahmoudinezhad & Akbar Karkhaneh
February 2016
29
Preparation and characterization of fiber-hydrogel composite as a cartilage tissue engineering scaffold
Fatemeh Mohabatpour & Akbar Karkhaneh
October 2015
30
Synthesis of a delivery system based on polyurethane and evaluation of sustained release of astatine products
Behnaz Sadat Eftekhari & Akbar Karkhaneh
September 2015
Books
#
Title
Author(s)
Publisher country
publication date
version
Portal Records
1
engineering of stealth nanocarriers in drug delivery
Akbar Karkhaneh, Nadia Shafaei, Nayereh Azimijou
Iran (Islamic Republic of)
December 2022
1
Journal Papers
Portal Records
1
Mina Maleki, Akbar Karkhaneh, Reza Karimi Soflou, "Raspberry-like PLA/PGS biodegradable microparticles with urethane linkages: Unlocking tailored release of magnesium ions and oxygen for bone tissue engineering", INTERNATIONAL JOURNAL OF PHARMACEUTICS, December 2023
Vol. 651,
Num. 1,
Page 1-15,
December 2023,
2
Nayereh Azimijou, Reza Karimi Soflou, Akbar Karkhaneh, "Actively targeted delivery of tamoxifen through stimuli-responsive polymeric nanoparticles for cancer chemotherapy", JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, July 2023
Vol. 87,
Num. 1,
Page 1-14,
July 2023,
3
Nadia Shafaei, Sajedeh Khorshidi Esfandabadi, Akbar Karkhaneh, "The immune-stealth polymeric coating on drug delivery nanocarriers: In vitro engineering and in vivo fate", JOURNAL OF BIOMATERIALS APPLICATIONS, July 2023
Vol. 0,
Num. 0,
Page 1-20,
July 2023,
4
Seyyed Ahmad Seyyed Nasrollah, Reza Karimi Soflou, Akbar Karkhaneh, "Photo-click crosslinked hydrogel containing MgO2-loaded PLGA microsphere with concurrent magnesium and oxygen release for bone tissue engineering", Materials Today Chemistry, February 2023
Vol. 28,
Num. 1,
Page 1-16,
February 2023,
5
Mina Shabani Samghabadi, Akbar Karkhaneh, Aliasghar Katbab, "Synthesis and characterization of biphasic layered structure composite with simultaneous electroconductive and piezoelectric behavior as a scaffold for bone tissue engineering", POLYMERS FOR ADVANCED TECHNOLOGIES, January 2023
Vol. 0,
Num. 0,
Page 1-14,
January 2023,
6
Reza Karimi Soflou, Akbar Karkhaneh, "Redox-Sensitive multifunctional hyaluronic acid-based nanomicelles with Fine-controlled anticancer drug release", INTERNATIONAL JOURNAL OF PHARMACEUTICS, November 2022
Vol. 629,
Num. 1,
Page 1-12,
November 2022,
7
Sajedeh Khorshidi Esfandabadi, Akbar Karkhaneh, "Cylindrical polyester/calcium peroxide oxygen-releasing microparticles: molecular dynamics simulation and experimental analyses", IRANIAN POLYMER JOURNAL, October 2022
Vol. 32,
Num. 1,
Page 45-58,
October 2022,
8
Reza Karimi Soflou, Akbar Karkhaneh, Iman Shabani, "Size-adjustable self-assembled nanoparticles through microfluidic platform promotes neuronal differentiation of mouse embryonic stem cells", Biomaterials Advances, July 2022
Vol. 140,
Num. 1,
Page 1-13,
July 2022,
9
Narges Akbari, Sajedeh Khorshidi Esfandabadi, Akbar Karkhaneh, "Effect of piezoelectricity of nanocomposite electrospun scaffold on cell behavior in bone tissue engineering", IRANIAN POLYMER JOURNAL, April 2022
Vol. 31,
Num. 8,
Page 919-930,
April 2022,
10
Mina Shabani Samghabadi, Akbar Karkhaneh, Aliasghar Katbab, "Synthesis and characterization of electroconductive hydrogels based on oxidized alginate and polypyrrole-grafted gelatin as tissue scaffolds", SOFT MATTER, August 2021
Vol. 17,
Num. 37,
Page 8465-8473,
August 2021,
11
Mohadeseh Hadizadeh, Mitra Naeimi, Mohammad Rafieinia, Akbar Karkhaneh, "A bifunctional electrospun nanocomposite wound dressing containing surfactin and curcumin: In vitro and in vivo studies", MATERIALS SCIENCE & ENGINEERING C, August 2021
Vol. 129,
Num. 1,
Page 1-11,
August 2021,
12
, Reza Karimi Soflou, Akbar Karkhaneh, "A hydrogel/particle composite with a gradient of oxygen releasing microparticle for concurrent osteogenic and chondrogenic differentiation in a single scaffold", COLLOIDS AND SURFACES B-BIOINTERFACES, July 2021
Vol. 207,
Num. 1,
Page 1-12,
July 2021,
13
Reza Karimi Soflou, Elham Mohseni Vadeghani, Akbar Karkhaneh, "Controlled release of resveratrol from a composite nanofibrous scaffold: Effect of resveratrol on antioxidant activity and osteogenic differentiation", JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, July 2021
Vol. 0,
Num. 0,
Page 1-10,
July 2021,
14
Marzie Sadat Moraveji, Hamid Keshvari, Akbar Karkhaneh, Shahin Bonakdar, Amin Hadi, Nooshin Haghighipour, "The effect of collagen/polycaprolactone fibrous scaffold decorated with graphene nanoplatelet and low-frequency electromagnetic field on neuronal gene expression by stem cells", Advances in Nano Research, June 2021
Vol. 10,
Num. 6,
Page 549-557,
June 2021,
15
Seyyed Ahmad Seyyed Nasrollah, Reza Karimi Soflou, Akbar Karkhaneh, "PEG-coated magnesium peroxide nanosheets with tunable microstructure: Effect of microstructure on concurrent oxygen and magnesium ion release", MATERIALS LETTERS, February 2021
Vol. 291,
Num. 1,
Page 1-5,
February 2021,
16
Fatemeh Imani, Reza Karimi Soflou, Iman Shabani, Akbar Karkhaneh, "PLA electrospun nanofibers modified with polypyrrole-grafted gelatin as bioactive electroconductive scaffold", POLYMER, January 2021
Vol. 218,
Num. 123478,
Page 1-11,
January 2021,
17
Reza Karimi Soflou, Sara Nejati, Akbar Karkhaneh, "Electroactive and antioxidant injectable in-situ forming hydrogels with tunable properties by polyethylenimine and polyaniline for nerve tissue engineering", COLLOIDS AND SURFACES B-BIOINTERFACES, January 2021
Vol. 199,
Num. 1,
Page 1-11,
January 2021,
18
Elham Mohseni Vadeghani, Reza Karimi Soflou, Akbar Karkhaneh, "Tunable hollow microspheres with a loading capacity of calcium phosphate nanoparticles as cell carriers: Effect of temperature and preparation conditions on microstructure", MATERIALS LETTERS, November 2020
Vol. 284,
Num. 1,
Page 1-4,
November 2020,
19
Misagh Saadipour, Akbar Karkhaneh, Masoumeh Haghbin Nazarpak, "An investigation into curcumin release from PLA particles loaded in PCL-GELATIN fibers for skin application", INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS, October 2020
Vol. 0,
Num. 0,
Page 1-10,
October 2020,
20
Sara Nejati, Reza Karimi Soflou, Akbar Karkhaneh, "Influence of process parameters on the characteristics of oxygen-releasing poly (lactic acid) microparticles
A multioptimization strategy", POLYMERS FOR ADVANCED TECHNOLOGIES, October 2020
Vol. 0,
Num. 0,
Page 1-13,
October 2020,
21
Elham Mohseni Vadeghani, Reza Karimi Soflou, Sajedeh Khorshidi Esfandabadi, Akbar Karkhaneh, "Fabrication of oxygen and calcium releasing microcarriers with different internal structures for bone tissue engineering: Solid filled versus hollow microparticles", COLLOIDS AND SURFACES B-BIOINTERFACES, September 2020
Vol. 197,
Num. 1,
Page 1-11,
September 2020,
22
Sajedeh Khorshidi Esfandabadi, Akbar Karkhaneh, "A hydrogel/particle composite with gradient in oxygen releasing microparticle for oxygenation of the cartilage-to-bone interface: Modeling and experimental viewpoints", MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, September 2020
Vol. 118,
Num. 1,
Page 1-12,
September 2020,
23
Alireza Mahjoubnia, Masoumeh Haghbin Nazarpak, Akbar Karkhaneh, "Polypyrrole-chitosan hydrogel reinforced with collagen-grafted PLA sub-micron fibers as an electrically responsive scaffold", INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS, September 2020
Vol. 0,
Num. 0,
Page 1-10,
September 2020,
24
Sara Nejati, Reza Karimi Soflou, Sajedeh Khorshidi Esfandabadi, Akbar Karkhaneh, "Development of an oxygen-releasing electroconductive in-situ crosslinkable hydrogel based on oxidized pectin and grafted gelatin for tissue engineering applications", COLLOIDS AND SURFACES B-BIOINTERFACES, September 2020
Vol. 196,
Num. 1,
Page 1-12,
September 2020,
25
Ziba Naghizadeh, Akbar Karkhaneh, Hanieh Nokhbatolfoghahaei, Saeed Farzad?Mohajeri, Maryam Rezai?Rad, Mohammad M. Dehghan, Pouyan Aminishakib, Arash Khojasteh, "Cartilage regeneration with dual-drug-releasing injectable hydrogel/microparticle system: In vitro and in vivo study", JOURNAL OF CELLULAR PHYSIOLOGY, August 2020
Vol. 0,
Num. 0,
Page 1-11,
August 2020,
26
Setayesh Yasami, Akbar Karkhaneh, Mohammad Ali Shokrgozar, Amir Amanzadeh, Majid Golkar, "Size effect of human epidermal growth factor-conjugated polystyrene particles on cell proliferation", Biomaterials Science, August 2020
Vol. 8,
Num. 1,
Page 4832-4840,
August 2020,
27
Sanaz Naghavi Alhosseini, Fathollah Moztarzadeh, Akbar Karkhaneh, "Genipin-cross-linked poly(vinyl alcohol) for neural scaffold", Bioinspired Biomimetic and Nanobiomaterials, March 2017
Vol. 0,
Num. 0,
Page 1-8,
March 2017,
28
Sajedeh Khorshidi, Atefeh Solouk Mofrad, Akbar Karkhaneh, Hamid Mirzadeh, Shahriar Sharifi, Saeideh Mazinani, "Effect of crosslinking procedure on structural, thermal, and functional performances of cellulosic nanofibers: A comparison between chemical and photochemical crosslinking", JOURNAL OF APPLIED POLYMER SCIENCE, May 2016
Vol. 0,
Num. 0,
Page 1-9,
May 2016,
29
, Erfan Dashtimoghadam, Rasool Nasseri Pourtakalo, Akbar Karkhaneh, Fatemeh Sadat Majedi, Nassir Mokarram, Philippe Renaud, Karl I. Jacob, "Cellulose nanowhiskers to regulate the microstructure of perfluorosulfonate ionomers for high-performance fuel cells", Journal of Materials Chemistry A, April 2014
Vol. 2,
Num. 29,
Page 11334-11340,
April 2014,
30
Akbar Karkhaneh, Ziba Naghizadeh, Mohammad Ali Shokrgozar, Shahin Bonakdar, Atefeh Solouk Mofrad, Nooshin Haghighipour, "Effects of hydrostatic pressure on biosynthetic activity
during chondrogenic differentiation of MSCs in hybrid
scaffolds", INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS, March 2014
Vol. 37,
Num. 2,
Page 142-148,
March 2014,
Conference Papers
Portal Records
1
Seyyed Ahmad Seyyed Nasrollah, Reza Karimi Soflou, Akbar Karkhaneh, "Fabrication of PLGA microcarriers with oxygen release capability for bone tissue engineering ", 15th International Seminar on Polymer Science and Technology (ISPST 2022), November 2022
2
Sara Nejati, Reza Karimi Soflou, Sajedeh Khorshidi Esfandabadi, Akbar Karkhaneh, "Preparation and Characterization of Oxygen-Releasing Nanocomposite Microspheres ", 8th International Conference on Nanostructures (ICNS8), November 2020
3
Misagh Saadipour, Akbar Karkhaneh, Masoumeh Haghbin Nazarpak, "An Investigation into curcumin release from PLA particles loaded in PCL gelatin fibres for skin applications ", 27th International Conference on Nanomedicine and Nanomaterials, May 2019
4
Pouria Rafsanjani Nejad, Akbar Karkhaneh, Ehsan Seyedjafari, S.Mehrdad Saviz, Iman Shabani, "Fabrication of Polypyrrole Coated Electrically Conductive Nanofibers for Tissue Engineering Applications ", 14th Congress on Stem Cell Biology and Technology, August 2018
5
Fatemeh Imani, Iman Shabani, Akbar Karkhaneh, "A new conducting nanofibrous scaffold for nerve tissue engineering applications ", The 1st International Iranian tissue Engineering and Regenerative Medicine congress :ITERM2018, July 2018
6
Ziba Naghizadeh, Akbar Karkhaneh, Mohammad Ali Shokrgozar, Shahin Bonakdar, Atefeh Solouk Mofrad, "Biomimetic Scaffold to Enhance Chondrogenic Differentiation of
Mesenchymal Stem Cells ", Royan International Twin Congress on Reproductive Biomedicine and Stem Cells Biology & Technology, September 2013
7
Ziba Naghizadeh, Akbar Karkhaneh, Mohammad Ali Shokrgozar, Shahin Bonakdar, Atefeh Solouk Mofrad, Noushin Haghighipour, "Effects
of Hydrostatic Pressure on Chondrocyte Biosynthesis in
Polycaprolactone-Polyvinyl Alcohol-Gelatin Scaffolds ", Royan International Twin Congress on Reproductive Biomedicine and Stem Cells Biology & Technology 9th, September 2013
Taught Courses
#
Course title
Description
Headlines
Date
1
Engineering Materials (I): Structure & Properties
The study of structure and properties of materials in engineering applications
Spring 2024
2
Fundamentals of Biocompatibility & Biological Tests
.
Spring 2024
3
Engineering Materials (I): Structure & Properties
The study of structure and properties of materials in engineering applications
Fall 2023
4
Protein Engineering
Understanding the structure of proteins and design of recombinant proteins
Fall 2023
5
Fundamentals of Biocompatibility & Biological Tests
.
Spring 2023
6
Engineering Materials (I): Structure & Properties
The study of structure and properties of materials in engineering applications
Spring 2023
7
Protein Engineering
Understanding the structure of proteins and design of recombinant proteins
Fall 2022
Inventions/Patents
#
Invention title
Reg. number
Country
contributers
Reg. date
Exp. date
1
Fabrication of chitosan polypyrol scaffold containing PLA fibers for nerve tissue engineering applications
103848
2021/02/1
2038/01/19